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Estrone is an endogenous steroidal hormone, which together with estradiol and estriol belongs to the group of hormones called estrogens.1 Estrogens are responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics. Estrogens also exhibit other functions including arterial vasodilation,2,3 reduction of intraocular pressure,4 and maintenance of bone density.3,4 In premenopausal women estrogen levels in plasma and urine vary cyclically, with a peak in the preovulatory phase. Estrone levels in plasma are 15-200 pg/ml with daily production be
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