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The Iron-Binding Capacity (IBC) test (also known as Total Iron-Binding Capacity (TIBC) test) is used to determine the total ability of serum to combine with excess ferric ions. The iron-binding protein in serum is known as siderophilin or transferrin, and normally is only partially filled with iron (in the form of ferric ions). The IBC test measures the total amount of iron which transferrin is capable of binding.
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